Drug Standards
Apexbio Technology LLC Imatinib (STI571) 152459-95-5 100mg
Imatinib (STI571) (CAS 152459-95-5) is a small-molecule inhibitor targeting protein tyrosine kinases including Abl kinase platelet-derived growth factor receptor (PDGFR) and c-Kit It modulates kinase activity by inhibiting phosphorylation thereby regulating oncogenic signal transduction pathways Imatinib exerts its biological activity primarily by suppressing the phosphorylation activity of Abl kinase (IC50 0 025 M) PDGFR (IC50 0 1 M) and c-Kit (IC50 0 1 M) In cell-based assays Imatinib inhibits PDGFR phosphorylation induced by PDGF-AA and PDGF-BB and reduces c-Kit-mediated signal transduction involved in tumor cell proliferation Based on these pharmacological properties Imatinib holds research potential in oncology for investigating kinase-driven cellular processes and therapeutic interventions
Medchemexpress LLC Atazanavir sulfate | 229975-97-7 | 802.93 | 1 ML
Atazanavir (BMS-232632) is a highly selective and orally active HIV-1 protease inhibitor. It acts as a substrate and inhibitor of CYP3A4, and an inhibitor of P-glycoprotein (P-gp). Atazanavir also inhibits SARS-CoV 3CL pro with an IC50 of 3.49 μM. Additionally, Atazanavir has been shown to inhibit cardiac fibrosis, hyperlipidemia, and induce malignant glioma cell death.
- Highly selective HIV-1 protease inhibitor
- Orally active
- Inhibits CYP3A4
- Inhibits P-glycoprotein (P-gp)
- Inhibits SARS-CoV 3CL pro
- Inhibits cardiac fibrosis
- Inhibits hyperlipidemia
- Induces malignant glioma death
![Alkali Scientific Folic Acid [Pteroylglutamic acid] [Vitamin M], 5 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000661364.jpg-250.jpg)
Alkali Scientific Folic Acid [Pteroylglutamic acid] [Vitamin M], 5 G
Folic Acid (Pteroylglutamic acid), also known as Vitamin B9, is a compound used in cell culture applications, supplied in a 5g quantity. Folic acid is essential for DNA synthesis, repair, and cellular division, making it a vital component in maintaining cell growth and function. In cell culture, folic acid is typically used to support the growth and proliferation of eukaryotic cells, particularly in mammalian cell culture systems. It is also utilized in research related to gene expression, cellular metabolism, and the study of folate metabolism in various biological systems. The 5g packaging is ideal for laboratories requiring consistent and stable folic acid supplementation in their cell culture medium.
Medchemexpress LLC 2,3,4,6-tetra-O-pivaloyl-alpha-D-glucopyranosyl bromide | 81058-27-7 | MFCD08275217 | 50g
Empagliflozin impurity 15 is an impurity of Empagliflozin (HY-15409)
Sigma Aldrich Fine Chemicals Biosciences Ascorbic acid European Pharmacopoeia (EP) Reference Standard | 50-81-7 | MFCD00064328
Ascorbic acid European Pharmacopoeia (EP) Reference StandardPurity: | MW: 176.12 | 50-81-7 | MFCD00064328
Sigma Aldrich Fine Chemicals Biosciences Prilocaine European Pharmacopoeia (EP) Reference Standard | 721-50-6 |
Prilocaine European Pharmacopoeia (EP) Reference Standard | Mol Wt: 220.31 | 721-50-6 |
Medchemexpress LLC Tenofovir (S-enantiomer) | 147127-19-3 | MFCD21604708 | 98.3% | 287.21 g/mol | C9H14N5O4P | 1 ML
(S)-Tenofovir is the S-enantiomer of tenofovir, a nucleotide reverse transcriptase inhibitor used in research on HIV and chronic hepatitis B. The product is supplied for research use and is available as a 10 mM solution in DMSO (1 mL) or as a solid in multiple mass sizes.
- S-enantiomer of tenofovir used in mechanistic and antiviral research
- Nucleotide reverse transcriptase inhibitor active against HIV and HBV
- Available as 10 mM solution in DMSO (1 mL) and solid formats (10 mg-500 mg)
- Chemical formula C9H14N5O4P and molecular weight 287.21 g/mol
- Reported purity approximately 98.3%
Medchemexpress LLC Trimetrexate glucuronate | 82952-64-5 | MFCD01725300 | 98.1% | 563.56 g·mol⁻¹ | C25H33N5O10 | 5 MG
Trimetrexate glucuronate is a folic acid antagonist that inhibits dihydrofolate reductase, interfering with DNA and RNA synthesis by preventing purine and thymidylate formation. It is supplied as a research reagent with reported purity of 98.09% and is provided as an off-white to light yellow solid. Recommended storage is 4°C in a sealed container; soluble in DMSO at 100 mg/mL (needs ultrasonic).
- inhibits dihydrofolate reductase (DHFR) and blocks nucleotide synthesis.
- reported purity of 98.09% for analytical and research use.
- solid form, off-white to light yellow appearance.
- soluble in DMSO (100 mg/mL) with ultrasonic assistance.
- recommended sealed storage at 4°C, protected from moisture.
Sigma Aldrich Fine Chemicals Biosciences Aripiprazole Related Compound G United States Pharmacopeia (USP) Reference Standard | 129722-25-4 | 25MG
Aripiprazole Related Compound G United States Pharmacopeia (USP) Reference Standard | Mol Wt: 446.37 | 129722-25-4 | 25MG
![Medchemexpress LLC 1-propanone, 1,3-bis[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl] | 1987905-93-0 | 5mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000266904.png-250.jpg)
Medchemexpress LLC 1-propanone, 1,3-bis[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl] | 1987905-93-0 | 5mg
Imatinib impurity 2 is an impurity of Imatinib (HY-15463)
Medchemexpress LLC Meta-fexofenadine | 479035-75-1 | MFCD21363595 | 98.6% | 501.66 | C32H39NO4 | 1 MG
Meta-fexofenadine is an analytical standard representing an impurity of fexofenadine, provided as an off-white to light-yellow solid for research and analytical applications. It is intended for use in pharmaceutical impurity profiling, analytical method development, and as a reference material; key chemical identifiers include CAS 479035-75-1, molecular formula C32H39NO4, and molecular weight 501.66.
- Purity 98.6% for reliable analytical reference.
- Supplied in small package sizes suitable for laboratory use.
- Solid form with off-white to light yellow appearance.
- Stable under recommended storage conditions for long-term use.
- Suitable for impurity profiling and method validation.
![Medchemexpress LLC 3-azabicyclo[3.1.0]hexane-2-carboxamide, N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl] | 394730-60-0 | MFCD22208555 | 98.5% | 519.7 g/mol | C27H45N5O5 | 200 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247172.png-250.jpg)
Medchemexpress LLC 3-azabicyclo[3.1.0]hexane-2-carboxamide, N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl] | 394730-60-0 | MFCD22208555 | 98.5% | 519.7 g/mol | C27H45N5O5 | 200 MG
Boceprevir (CAS 394730-60-0) is a small-molecule inhibitor of the HCV NS3 protease used for biochemical and cell-based research applications. It is supplied as a research-grade solid with a high reported purity suitable for experimental assays.
- High purity suitable for research use.
- Molecular weight 519.7 g/mol.
- Chemical formula C27H45N5O5.
- Intended for biochemical and cell-based assays targeting viral protease activity.
- Available as a 200 MG pack size.
Medchemexpress LLC Methocarbamol | 532-03-6 | >99.8% | 50 MG
Methocarbamol is an orally active central muscle relaxant. It blocks the muscular Nav1.4 channel and reversibly affects its voltage dependence of inactivation.
- Potential for research into muscle spasms and pain syndromes
- Orally active central muscle relaxant
- Blocks muscular Nav1.4 channel
Medchemexpress LLC Osimertinib dimesylate | 2070014-82-1 | 99.19% | C30H41N7O8S2 | 200 MG
Osimertinib dimesylate (AZD-9291 dimesylate) is an irreversible and mutant-selective EGFR inhibitor. It demonstrates potent inhibitory activity against key EGFR mutations, including T790M, with high efficacy in tumor models. This product is for research use only.
- Mutant selective EGFR inhibitor
- Irreversible binding action
- Potent inhibition against EGFR mutations
- Improved pharmacokinetic profile
- Broad chemical and profile diversity
- Proven efficacy in tumor models